Troponin yog ib qho kev tswj hwm cov protein ntawm cov nqaij fibers hauv cov leeg nqaij, uas feem ntau tswj cov txheeb ze zawv zawg ntawm cov nqaij tuab thiab nyias nyias thaum lub sij hawm myocardial contraction.Nws yog tsim los ntawm peb subunits: troponin T (TNT), troponin I (TNI) thiab troponin C (TNC).Kev nthuav qhia ntawm peb hom subtypes hauv cov leeg pob txha thiab myocardium kuj tseem tswj hwm los ntawm cov noob sib txawv.Cov ntsiab lus ntawm plawv troponin hauv cov ntshav ib txwm muaj qis dua li ntawm lwm cov enzymes myocardial, tab sis cov concentration hauv cardiomyocytes siab heev.Thaum lub myocardial cell membrane tsis zoo, cTnI tsis tuaj yeem nkag mus rau lub cell membrane rau hauv cov ntshav.Thaum cov hlwb myocardial raug degeneration thiab necrosis vim ischemia thiab hypoxia, cTnI raug tso rau hauv cov ntshav los ntawm cov cell membrane puas.Qhov siab ntawm cTnI pib nce 3-4 teev tom qab qhov tshwm sim ntawm AMI, nce siab ntawm 12-24 teev, thiab txuas ntxiv rau 5-10 hnub.Yog li ntawd, kev txiav txim siab ntawm cTnI concentration hauv cov ntshav tau dhau los ua qhov taw qhia zoo rau kev soj ntsuam ntawm qhov ua tau zoo ntawm kev rov ua dua thiab rov ua dua tshiab hauv AMI cov neeg mob.cTnI tsis tsuas yog muaj qhov tshwj xeeb muaj zog, tab sis kuj tseem muaj qhov rhiab heev thiab ntev ntev.Yog li, cTnI tuaj yeem siv los ua tus cim tseem ceeb los pab rau kev kuaj mob myocardial raug mob, tshwj xeeb tshaj yog mob myocardial infarction.
Microparticles (M): | 0.13mg / ml Microparticles ua ke nrog cov tshuaj tiv thaiv troponin I ultra antibody |
Reagent 1 (R1): | 0.1M Tris tsis |
Reagent 2 (R2): | 0.5μg / ml Alkaline phosphatase sau npe antitroponin I ultra |
Kev ntxuav tu: | 0.05% surfactant, 0.9% Sodium chloride tsis |
Substrate: | AMPPD hauv AMP tsis |
Calibrator (yeem): | Troponin kuv ultra antigen |
Tswj cov ntaub ntawv (yeem): | Troponin kuv ultra antigen |
Nco tseg:
1.Cov khoom tsis sib hloov ntawm cov khoom siv reagent strips;
2.Saib lub calibrator lub raj mis daim ntawv lo rau calibrator concentration;
3.Saib lub raj mis tswj daim ntawv lo rau qhov concentration ntau ntawm kev tswj.
1. Cia: 2 ℃ ~ 8 ℃, tsis txhob tshav ntuj ncaj qha.
2.Kev siv tau: cov khoom tsis tau qhib tau siv tau rau 12 lub hlis raws li cov xwm txheej tau teev tseg.
3.Calibrators thiab tswj tom qab dissolving tuaj yeem khaws cia rau 14 hnub hauv 2 ℃ ~ 8 ℃ qhov tsaus ntuj.
Automated CLIA System ntawm Illumaxbio (lumiflx16, lumiflx16s, lumilite8, lumilite8s).